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L-DOPS corrects neurochemical abnormalities in a Menkes disease mouse model
OBJECTIVE: Menkes disease is a lethal neurodegenerative disorder of infancy caused by mutations in a copper-transporting ATPase gene, ATP7A. Among its multiple cellular tasks, ATP7A transfers copper to dopamine-beta-hydroxylase (DBH) within the lumen of the Golgi network or secretory granules, catal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597755/ https://ncbi.nlm.nih.gov/pubmed/23224983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23787 |
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