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Metallothionein messenger RNA regulation in the mottled mouse and Menkes kinky hair syndrome.

Menkes kinky hair syndrome is an X-linked neurodegenerative disorder, causing tissue-specific increases in copper and metallothionein content. A mouse model is provided by hemizygotes for mutant alleles at the X-linked mottled locus. Herein we test the possibility that the primary defect in both spe...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Packman, S, Palmiter, R D, Karin, M, O'Toole, C
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1987
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424381/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3571489/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112959
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