Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood and adolescence. Despite advances in therapy, patients with histological variant of rhabdomyosarcoma known as alveolar rhabdomyosarcoma (ARMS) have a 5-year survival of less than 30%. Caveolin-1 (CAV1), encoding the structural comp...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Huertas-Martínez, Juan, Rello-Varona, Santiago, Herrero-Martín, David, Barrau, Ignasi, García-Monclús, Silvia, Sáinz-Jaspeado, Miguel, Lagares-Tena, Laura, Núñez-Álvarez, Yaiza, Mateo-Lozano, Silvia, Mora, Jaume, Roma, Josep, Toran, Nuria, Moran, Sebastian, López-Alemany, Roser, Gallego, Soledad, Esteller, Manel, Peinado, Miguel A., Xavier García del, Muro, Tirado, Oscar M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259434/
https://ncbi.nlm.nih.gov/pubmed/25313138
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