Caveolin-1 is down-regulated in alveolar rhabdomyosarcomas and negatively regulates tumor growth

Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood and adolescence. Despite advances in therapy, patients with histological variant of rhabdomyosarcoma known as alveolar rhabdomyosarcoma (ARMS) have a 5-year survival of less than 30%. Caveolin-1 (CAV1), encoding the structural comp...

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Publicat a:Oncotarget
Autors principals: Huertas-Martínez, Juan, Rello-Varona, Santiago, Herrero-Martín, David, Barrau, Ignasi, García-Monclús, Silvia, Sáinz-Jaspeado, Miguel, Lagares-Tena, Laura, Núñez-Álvarez, Yaiza, Mateo-Lozano, Silvia, Mora, Jaume, Roma, Josep, Toran, Nuria, Moran, Sebastian, López-Alemany, Roser, Gallego, Soledad, Esteller, Manel, Peinado, Miguel A., Xavier García del, Muro, Tirado, Oscar M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259434/
https://ncbi.nlm.nih.gov/pubmed/25313138
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