Phosphorylation of Ribosomal Protein S6 Kinase 1 at Thr421/Ser424 and Dephosphorylation at Thr389 Regulates SP600125-Induced Polyploidization of Megakaryocytic Cell Lines

Megakaryocytes (MKs) are one of the few cell types that become polyploid; however, the mechanisms by which these cells are designated to become polyploid are not fully understood. In this investigation, we successfully established two relatively synchronous polyploid cell models by inducing Dami and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Chang-Ling, Yang, Jin-Gang, Lin, Di, Zhao, Yong-Shan, Liu, Shuo, Xing, Si-Ning, Zhao, Song, Chen, Cong-Qin, Jiang, Zhi-Ming, Pu, Fei-Fei, Cao, Jian-Ping, Ma, Dong-Chu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259319/
https://ncbi.nlm.nih.gov/pubmed/25486532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114389
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