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Protein Phosphatase 1-α Regulates AS160 Ser(588) and Thr(642) Dephosphorylation in Skeletal Muscle

Akt substrate of 160 kDa (AS160) phosphorylation on Thr(642) and Ser(588) by Akt is essential for insulin’s full effect on glucose transport. However, protein phosphorylation is determined by the balance of actions by kinases and phosphatases, and the specific phosphatase(s) controlling AS160 dephos...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Sharma, Pragya, Arias, Edward B., Cartee, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001182/
https://ncbi.nlm.nih.gov/pubmed/27246912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-0867
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