Myeloid-Derived Suppressor Cells as Therapeutic Target in Hematological Malignancies

Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature myeloid cells that accumulate during pathological conditions such as cancer and are associated with a poor clinical outcome. MDSC expansion hampers the host anti-tumor immune response by inhibition of T cell prolifera...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: De Veirman, Kim, Van Valckenborgh, Els, Lahmar, Qods, Geeraerts, Xenia, De Bruyne, Elke, Menu, Eline, Van Riet, Ivan, Vanderkerken, Karin, Van Ginderachter, Jo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258607/
https://ncbi.nlm.nih.gov/pubmed/25538893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00349
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