Mechanistically different catalytic antibodies obtained from immunization with a single transition-state analog.
The variable-region peptide sequence and steady-state kinetic behavior are compared for a family of catalytic antibodies that arose from the same immune response to a transition-state analog. The crystal structure of the most catalytically active member of the family (17E8) has been solved to 2.5 A...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1995
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7878042/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1694 |
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