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Mechanistically different catalytic antibodies obtained from immunization with a single transition-state analog.

The variable-region peptide sequence and steady-state kinetic behavior are compared for a family of catalytic antibodies that arose from the same immune response to a transition-state analog. The crystal structure of the most catalytically active member of the family (17E8) has been solved to 2.5 A...

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Библиографические подробности
Главные авторы: Guo, J, Huang, W, Zhou, G W, Fletterick, R J, Scanlan, T S
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC42586/
https://ncbi.nlm.nih.gov/pubmed/7878042
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