A common ancestry for multiple catalytic antibodies generated against a single transition-state analog.
Immunization with a single haptenic transition-state analog generates a few catalytic antibodies among the dozens of antibodies capable of binding the hapten. The diversity of the immune response has raised some fundamental issues, such as How do catalytic and noncatalytic antibodies differ on a str...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.6045 |
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