Lethal Factor, but Not Edema Factor, Is Required to Cause Fatal Anthrax in Cynomolgus Macaques after Pulmonary Spore Challenge

Inhalational anthrax is caused by inhalation of Bacillus anthracis spores. The ability of B. anthracis to cause anthrax is attributed to the plasmid-encoded A/B-type toxins, edema toxin (edema factor and protective antigen) and lethal toxin (lethal factor and protective antigen), and a poly-d-glutam...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Hutt, Julie A., Lovchik, Julie A., Drysdale, Melissa, Sherwood, Robert L., Brasel, Trevor, Lipscomb, Mary F., Lyons, C. Rick
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2014
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258508/
https://ncbi.nlm.nih.gov/pubmed/25285720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.008
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