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Toxin-Deficient Mutants of Bacillus anthracis Are Lethal in a Murine Model for Pulmonary Anthrax

Bacillus anthracis, the etiologic agent of anthrax, produces at least three primary virulence factors: lethal toxin, edema toxin, and a capsule. The capsule is absolutely required for dissemination and lethality in a murine model of inhalation anthrax, yet the roles for the toxins during infection a...

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Detalhes bibliográficos
Main Authors: Heninger, Sara, Drysdale, Melissa, Lovchik, Julie, Hutt, Julie, Lipscomb, Mary F., Koehler, Theresa M., Lyons, C. Rick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1695493/
https://ncbi.nlm.nih.gov/pubmed/16923785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00719-06
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