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Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax

Bacillus anthracis, the agent of anthrax, produces a poly-D-glutamic acid capsule that has been implicated in virulence. Many strains missing pXO2 (96 kb), which harbors the capsule biosynthetic operon capBCAD, but carrying pXO1 (182 kb) that harbors the anthrax toxin genes, are attenuated in animal...

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Detalhes bibliográficos
Main Authors: Drysdale, Melissa, Heninger, Sara, Hutt, Julie, Chen, Yahua, Lyons, C Rick, Koehler, Theresa M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC544908/
https://ncbi.nlm.nih.gov/pubmed/15616593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600495
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