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Capsule synthesis by Bacillus anthracis is required for dissemination in murine inhalation anthrax

Bacillus anthracis, the agent of anthrax, produces a poly-D-glutamic acid capsule that has been implicated in virulence. Many strains missing pXO2 (96 kb), which harbors the capsule biosynthetic operon capBCAD, but carrying pXO1 (182 kb) that harbors the anthrax toxin genes, are attenuated in animal...

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Autors principals: Drysdale, Melissa, Heninger, Sara, Hutt, Julie, Chen, Yahua, Lyons, C Rick, Koehler, Theresa M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC544908/
https://ncbi.nlm.nih.gov/pubmed/15616593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600495
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