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Lethal Factor, but Not Edema Factor, Is Required to Cause Fatal Anthrax in Cynomolgus Macaques after Pulmonary Spore Challenge

Inhalational anthrax is caused by inhalation of Bacillus anthracis spores. The ability of B. anthracis to cause anthrax is attributed to the plasmid-encoded A/B-type toxins, edema toxin (edema factor and protective antigen) and lethal toxin (lethal factor and protective antigen), and a poly-d-glutam...

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Publicado en:Am J Pathol
Autores principales: Hutt, Julie A., Lovchik, Julie A., Drysdale, Melissa, Sherwood, Robert L., Brasel, Trevor, Lipscomb, Mary F., Lyons, C. Rick
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258508/
https://ncbi.nlm.nih.gov/pubmed/25285720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.008
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