Lethal Factor, but Not Edema Factor, Is Required to Cause Fatal Anthrax in Cynomolgus Macaques after Pulmonary Spore Challenge

Inhalational anthrax is caused by inhalation of Bacillus anthracis spores. The ability of B. anthracis to cause anthrax is attributed to the plasmid-encoded A/B-type toxins, edema toxin (edema factor and protective antigen) and lethal toxin (lethal factor and protective antigen), and a poly-d-glutam...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Hutt, Julie A., Lovchik, Julie A., Drysdale, Melissa, Sherwood, Robert L., Brasel, Trevor, Lipscomb, Mary F., Lyons, C. Rick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258508/
https://ncbi.nlm.nih.gov/pubmed/25285720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.008
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