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STING contributes to anti-glioma immunity via triggering type-I IFN signals in the tumor microenvironment

While type-I interferons (IFN) play critical roles in antiviral and antitumor activity, it remains to be elucidated how type-I IFNs are produced in sterile conditions of the tumor microenvironment and directly impacts tumor-infiltrating immune cells. Mouse de novo gliomas show increased expression o...

詳細記述

保存先:
書誌詳細
出版年:Cancer Immunol Res
主要な著者: Ohkuri, Takayuki, Ghosh, Arundhati, Kosaka, Akemi, Zhu, Jianzhong, Ikeura, Maki, David, Michael, Watkins, Simon C., Sarkar, Saumendra N, Okada, Hideho
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258479/
https://ncbi.nlm.nih.gov/pubmed/25300859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0099
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