Protective role of STING against gliomagenesis: Rational use of STING agonist in anti-glioma immunotherapy

We recently reported that STING contributes to antiglioma immunity by triggering type I IFN induction in glioma microenvironment. Moreover, intratumoral administration of STING agonist improved the efficacy of peptide vaccination in a mouse glioma model, suggesting the rational use of STING agonists...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Ohkuri, Takayuki, Ghosh, Arundhati, Kosaka, Akemi, Sarkar, Saumendra N, Okada, Hideho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485761/
https://ncbi.nlm.nih.gov/pubmed/26137417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.999523
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