STING contributes to anti-glioma immunity via triggering type-I IFN signals in the tumor microenvironment

While type-I interferons (IFN) play critical roles in antiviral and antitumor activity, it remains to be elucidated how type-I IFNs are produced in sterile conditions of the tumor microenvironment and directly impacts tumor-infiltrating immune cells. Mouse de novo gliomas show increased expression o...

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Publicat a:Cancer Immunol Res
Autors principals: Ohkuri, Takayuki, Ghosh, Arundhati, Kosaka, Akemi, Zhu, Jianzhong, Ikeura, Maki, David, Michael, Watkins, Simon C., Sarkar, Saumendra N, Okada, Hideho
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258479/
https://ncbi.nlm.nih.gov/pubmed/25300859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0099
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