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Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery
Penicillin and related beta-lactams comprise one of our oldest and most widely used antibiotic therapies. These drugs have long been known to target enzymes called penicillin-binding proteins (PBPs) that build the bacterial cell wall. Investigating the downstream consequences of target inhibition an...
Shranjeno v:
| izdano v: | Cell |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258230/ https://ncbi.nlm.nih.gov/pubmed/25480295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.11.017 |
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