Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types

Major histocompatibility class II (MHC-II) expression is critical for immune responses and is controlled by the MHC-II transactivator CIITA. CIITA is primarily regulated at the transcriptional level and is expressed from three main promoters with myeloid, lymphoid, and IFN-γ treated non-hematopoieti...

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Publicado en:Genes Immun
Autores principales: Lohsen, Sarah, Majumder, Parimal, Scharer, Christopher D., Barwick, Benjamin G., Austin, James W., Zinzow-Kramer, Wendy M., Boss, Jeremy M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257854/
https://ncbi.nlm.nih.gov/pubmed/25101797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.49
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