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CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments
Three distinct promoters control the master regulator of MHC class II expression, CIITA, in a cell type specific manner. Promoter I (pI) CIITA, expressed primarily by dendritic cells and macrophages, expresses a unique isoform that contains a caspase recruitment domain. The activity and function of...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366023/ https://ncbi.nlm.nih.gov/pubmed/22218223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2011.86 |
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