Advantages of Foxp3(+) regulatory T cell depletion using DEREG mice

Several mechanisms enable immunological self-tolerance. Regulatory T cells (Tregs) are a specialized T cell subset that prevents autoimmunity and excessive immune responses, but can also mediate detrimental tolerance to tumors and pathogens in a Foxp3-dependent manner. Genetic tools exploiting the f...

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Vydáno v:Immun Inflamm Dis
Hlavní autoři: Mayer, Christian T, Lahl, Katharina, Milanez-Almeida, Pedro, Watts, Deepika, Dittmer, Ulf, Fyhrquist, Nanna, Huehn, Jochen, Kopf, Manfred, Kretschmer, Karsten, Rouse, Barry, Sparwasser, Tim
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257761/
https://ncbi.nlm.nih.gov/pubmed/25505550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.33
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