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Limitations of Foxp3(+) Treg depletion following viral infection in DEREG mice

Regulatory T cells (Tregs) play a critical role in maintaining tissue homeostasis and preventing the development of immunopathology. Depletion of REGulatory T cell (DEREG) mice express a diphtheria toxin receptor (DTR)-eGFP transgene under the control of the Foxp3 promoter allowing for Treg depletio...

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Détails bibliographiques
Auteurs principaux: Christiaansen, Allison F., Boggiatto, Paola M., Varga, Steven M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029878/
https://ncbi.nlm.nih.gov/pubmed/24642426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.03.005
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