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Limitations of Foxp3(+) Treg depletion following viral infection in DEREG mice
Regulatory T cells (Tregs) play a critical role in maintaining tissue homeostasis and preventing the development of immunopathology. Depletion of REGulatory T cell (DEREG) mice express a diphtheria toxin receptor (DTR)-eGFP transgene under the control of the Foxp3 promoter allowing for Treg depletio...
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Auteurs principaux: | , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4029878/ https://ncbi.nlm.nih.gov/pubmed/24642426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.03.005 |
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