Rapid Rebound of the Treg Compartment in DEREG Mice Limits the Impact of Treg Depletion on Mycobacterial Burden, but Prevents Autoimmunity

The development of an effective vaccine against tuberculosis (Tb) represents one of the major medical challenges of this century. Mycobacterium bovis Bacille Calmette-Guerin (BCG), the only vaccine available at present, is mostly effective at preventing disseminated Tb in children, but shows variabl...

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Detalhes bibliográficos
Main Authors: Berod, Luciana, Stüve, Philipp, Varela, Filipa, Behrends, Jochen, Swallow, Maxine, Kruse, Friederike, Krull, Freyja, Ghorbani, Peyman, Mayer, Christian T., Hölscher, Christoph, Sparwasser, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106855/
https://ncbi.nlm.nih.gov/pubmed/25050936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102804
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