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Optimal Isolation of Functional Foxp3(+) Induced Regulatory T Cells Using DEREG Mice
Foxp3 reporter mice including DEREG (DEpletion of REGulatory T cells) mice have greatly helped in exploring the biology of Foxp3(+) Tregs. DEREG mice express a DTR-eGFP fusion protein under the control of a bacterial artificial chromosome (BAC)-encoded Foxp3 promoter, allowing the viable isolation a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434173/ https://ncbi.nlm.nih.gov/pubmed/22957107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044760 |
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