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Extended Ultrastructural Characterization of Chordoma Cells: The Link to New Therapeutic Options

Chordomas are rare bone tumors, developed from the notochord and largely resistant to chemotherapy. A special feature of this tumor is the heterogeneity of its cells. By combining high pressure freezing (HPF) with electron tomography we were able to illustrate the connections within the cells, the c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Kolb, Dagmar, Pritz, Elisabeth, Steinecker-Frohnwieser, Bibiane, Lohberger, Birgit, Deutsch, Alexander, Kroneis, Thomas, El-Heliebi, Amin, Dohr, Gottfried, Meditz, Katharina, Wagner, Karin, Koefeler, Harald, Leitinger, Gerd, Leithner, Andreas, Liegl-Atzwanger, Bernadette, Zweytick, Dagmar, Rinner, Beate
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257693/
https://ncbi.nlm.nih.gov/pubmed/25479055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114251
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