Extended Ultrastructural Characterization of Chordoma Cells: The Link to New Therapeutic Options

Chordomas are rare bone tumors, developed from the notochord and largely resistant to chemotherapy. A special feature of this tumor is the heterogeneity of its cells. By combining high pressure freezing (HPF) with electron tomography we were able to illustrate the connections within the cells, the c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kolb, Dagmar, Pritz, Elisabeth, Steinecker-Frohnwieser, Bibiane, Lohberger, Birgit, Deutsch, Alexander, Kroneis, Thomas, El-Heliebi, Amin, Dohr, Gottfried, Meditz, Katharina, Wagner, Karin, Koefeler, Harald, Leitinger, Gerd, Leithner, Andreas, Liegl-Atzwanger, Bernadette, Zweytick, Dagmar, Rinner, Beate
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257693/
https://ncbi.nlm.nih.gov/pubmed/25479055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114251
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