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Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer
Cancer genome characterization has revealed driver mutations in genes that govern ubiquitylation; however, the mechanisms by which these alterations promote tumorigenesis remain incompletely characterized. Here, we analyzed changes in the ubiquitin landscape induced by prostate cancer-associated mut...
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| Wydane w: | Science |
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| Główni autorzy: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4257137/ https://ncbi.nlm.nih.gov/pubmed/25278611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1250255 |
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