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Enhanced local bioavailability of single or compound drugs delivery to the inner ear through application of PLGA nanoparticles via round window administration

In this paper, the potential of poly(d,l-lactide-co-glycolide acid) (PLGA) nanoparticles (NPs) for carrying single or compound drugs traversing the round window membrane (RWM) was examined after the round window (RW) administration of different NPs to guinea pigs. First, coumarin-6 was incorporated...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Cai, Hui, Wen, Xingxing, Wen, Lu, Tirelli, Nicola, Zhang, Xiao, Zhang, Yue, Su, Huanpeng, Yang, Fan, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257110/
https://ncbi.nlm.nih.gov/pubmed/25489245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S72555
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