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Antifungal amphiphilic aminoglycoside K20: bioactivities and mechanism of action

K20 is a novel amphiphilic antifungal aminoglycoside that is synthetically derived from the antibiotic kanamycin A. Reported here are investigations of K20′s antimicrobial activities, cytotoxicity, and fungicidal mechanism of action. In vitro growth inhibitory activities against a variety of human a...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Shrestha, Sanjib K., Chang, Cheng-Wei T., Meissner, Nicole, Oblad, John, Shrestha, Jaya P., Sorensen, Kevin N., Grilley, Michelle M., Takemoto, Jon Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257101/
https://ncbi.nlm.nih.gov/pubmed/25538692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00671
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