Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy

Current treatments for diabetic nephropathy (DN) only result in slowing its progression, thus highlighting a need to identify novel targets. Increased production of reactive oxygen species (ROS) is considered a key downstream pathway of end‐organ injury with increasing data implicating both mitochon...

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Vydáno v:Physiol Rep
Hlavní autoři: Thallas‐Bonke, Vicki, Jha, Jay C., Gray, Stephen P., Barit, David, Haller, Hermann, Schmidt, Harald H.H.W., Coughlan, Melinda T., Cooper, Mark E., Forbes, Josephine M., Jandeleit‐Dahm, Karin A.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Periodicals, Inc. 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255803/
https://ncbi.nlm.nih.gov/pubmed/25367693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12192
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