Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy

AIMS/HYPOTHESIS: Changes in podocyte morphology and function are associated with albuminuria and progression of diabetic nephropathy NADPH oxidase 4 (NOX4) is the main source of reactive oxygen species (ROS) in the kidney and Nox4 is upregulated in podocytes in response to high glucose. We assessed...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Diabetologia
Egile Nagusiak: Jha, Jay C., Thallas-Bonke, Vicki, Banal, Claudine, Gray, Stephen P., Chow, Bryna S. M., Ramm, Georg, Quaggin, Susan E., Cooper, Mark E., Schmidt, Harald H. H. W., Jandeleit-Dahm, Karin A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450410/
https://ncbi.nlm.nih.gov/pubmed/26508318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3796-0
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