Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy

AIMS/HYPOTHESIS: Changes in podocyte morphology and function are associated with albuminuria and progression of diabetic nephropathy NADPH oxidase 4 (NOX4) is the main source of reactive oxygen species (ROS) in the kidney and Nox4 is upregulated in podocytes in response to high glucose. We assessed...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Jha, Jay C., Thallas-Bonke, Vicki, Banal, Claudine, Gray, Stephen P., Chow, Bryna S. M., Ramm, Georg, Quaggin, Susan E., Cooper, Mark E., Schmidt, Harald H. H. W., Jandeleit-Dahm, Karin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450410/
https://ncbi.nlm.nih.gov/pubmed/26508318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3796-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados