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Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality

Large shifts of osmolality occur in the kidney medulla as part of the urine concentrating mechanism. Hyperosmotic stress profoundly challenges cellular homeostasis and induces endoplasmic reticulum (ER) stress. Here, we examined the unfolded protein response (UPR) in hyperosmotically‐challenged prin...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Physiol Rep
Päätekijät: Crambert, Gilles, Ernandez, Thomas, Lamouroux, Christine, Roth, Isabelle, Dizin, Eva, Martin, Pierre‐Yves, Féraille, Eric, Hasler, Udo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Wiley Periodicals, Inc. 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255800/
https://ncbi.nlm.nih.gov/pubmed/25413317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12169
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