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Transcriptional and epigenetic regulation of T-helper lineage specification

Combined with TCR stimuli, extracellular cytokine signals initiate the differentiation of naive CD4(+) T cells into specialized effector T-helper (Th) and regulatory T (Treg) cell subsets. The lineage specification and commitment process occurs through the combinatorial action of multiple transcript...

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Bibliografiske detaljer
Udgivet i:Immunol Rev
Main Authors: Tripathi, Subhash K, Lahesmaa, Riitta
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255756/
https://ncbi.nlm.nih.gov/pubmed/25123277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12204
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