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Transcriptional and epigenetic regulation of T-helper lineage specification
Combined with TCR stimuli, extracellular cytokine signals initiate the differentiation of naive CD4(+) T cells into specialized effector T-helper (Th) and regulatory T (Treg) cell subsets. The lineage specification and commitment process occurs through the combinatorial action of multiple transcript...
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| Veröffentlicht in: | Immunol Rev |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255756/ https://ncbi.nlm.nih.gov/pubmed/25123277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12204 |
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