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Distinct Subcellular Trafficking Resulting from Monomeric vs Multimeric Targeting to Endothelial ICAM-1: Implications for Drug Delivery
[Image: see text] Ligand-targeted, receptor-mediated endocytosis is commonly exploited for intracellular drug delivery. However, cells-surface receptors may follow distinct endocytic fates when bound by monomeric vs multimeric ligands. Our purpose was to study this paradigm using ICAM-1, an endothel...
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| Publicado en: | Mol Pharm |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255724/ https://ncbi.nlm.nih.gov/pubmed/25301142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500409y |
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