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Intra- and Trans-Cellular Delivery of Enzymes by Direct Conjugation with Non-Multivalent Anti-ICAM Molecules

Intercellular adhesion molecule 1 (ICAM-1) is a cell-surface protein overexpressed in many diseases and explored for endocytosis and transcytosis of drug delivery systems. All previous evidence demonstrating ICAM-1-mediated transport of therapeutics into or across cells was obtained using nanocarrie...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Ghaffarian, Rasa, Roki, Niksa, Abouzeid, Abraham, Vreeland, Wyatt, Muro, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830118/
https://ncbi.nlm.nih.gov/pubmed/27473764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.07.042
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