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Developmental Control of the Melanocortin-4 Receptor by MRAP2 Proteins in Zebrafish
The melanocortin-4 receptor (MC4R) is essential for control of energy homeostasis in vertebrates. MC4R interacts with melanocortin receptor accessory protein 2 (MRAP2) in vitro, but its functions in vivo are unknown. We found that MRAP2a, a larval form, stimulates growth of zebrafish by specifically...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4255277/ https://ncbi.nlm.nih.gov/pubmed/23869017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1232995 |
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