P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy

Extracellular nucleotides via activation of P2 purinergic receptors influence hepatocyte proliferation and liver regeneration in response to 70% partial hepatectomy (PH). Adult hepatocytes express multiple P2Y (G protein-coupled) and P2X (ligand-gated ion channels) purinergic receptor subtypes. Howe...

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Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Tackett, Bryan C., Sun, Hongdan, Mei, Yu, Maynard, Janielle P., Cheruvu, Sayuri, Mani, Arunmani, Hernandez-Garcia, Andres, Vigneswaran, Nadarajah, Karpen, Saul J., Thevananther, Sundararajah
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Liver and Biliary Tract
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254960/
https://ncbi.nlm.nih.gov/pubmed/25301185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00092.2014
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