Transferrin receptor 2 is crucial for iron sensing in human hepatocytes

Hepcidin expression in vivo is regulated in proportion to iron status (i.e., increased by iron loading and decreased in iron deficiency). However, in vitro studies with hepatoma cell lines often show an inverse relationship between iron status and hepcidin expression. Here, we investigated possible...

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Bibliographic Details
Main Authors: Rapisarda, Chiara, Puppi, Juliana, Hughes, Robin D., Dhawan, Anil, Farnaud, Sebastien, Evans, Robert W., Sharp, Paul A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
Subjects:
Liver and Biliary Tract
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950680/
https://ncbi.nlm.nih.gov/pubmed/20576915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00157.2010
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