Transferrin receptor 2 is crucial for iron sensing in human hepatocytes

Hepcidin expression in vivo is regulated in proportion to iron status (i.e., increased by iron loading and decreased in iron deficiency). However, in vitro studies with hepatoma cell lines often show an inverse relationship between iron status and hepcidin expression. Here, we investigated possible...

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Detalhes bibliográficos
Main Authors: Rapisarda, Chiara, Puppi, Juliana, Hughes, Robin D., Dhawan, Anil, Farnaud, Sebastien, Evans, Robert W., Sharp, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950680/
https://ncbi.nlm.nih.gov/pubmed/20576915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00157.2010
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