P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy

Extracellular nucleotides via activation of P2 purinergic receptors influence hepatocyte proliferation and liver regeneration in response to 70% partial hepatectomy (PH). Adult hepatocytes express multiple P2Y (G protein-coupled) and P2X (ligand-gated ion channels) purinergic receptor subtypes. Howe...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Tackett, Bryan C., Sun, Hongdan, Mei, Yu, Maynard, Janielle P., Cheruvu, Sayuri, Mani, Arunmani, Hernandez-Garcia, Andres, Vigneswaran, Nadarajah, Karpen, Saul J., Thevananther, Sundararajah
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Liver and Biliary Tract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254960/
https://ncbi.nlm.nih.gov/pubmed/25301185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00092.2014
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