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A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using Photocrosslinking and Click Chemistry

Plasmodium falciparum is responsible for severe malaria which is one of the most prevalent and deadly infectious diseases in the world. The antimalarial therapeutic arsenal is hampered by the onset of resistance to all known pharmacological classes of compounds, so new drugs with novel mechanisms of...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Penarete-Vargas, Diana Marcela, Boisson, Anaïs, Urbach, Serge, Chantelauze, Hervé, Peyrottes, Suzanne, Fraisse, Laurent, Vial, Henri J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254740/
https://ncbi.nlm.nih.gov/pubmed/25470252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113918
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