Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate

BACKGROUND AND PURPOSE: Choline analogues, a new type of antimalarials, exert potent in vitro and in vivo antimalarial activity. This has given rise to albitiazolium, which is currently in phase II clinical trials to cure severe malaria. Here we dissected its mechanism of action step by step from ch...

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Detalhes bibliográficos
Main Authors: Wein, S, Maynadier, M, Bordat, Y, Perez, J, Maheshwari, S, Bette-Bobillo, P, Tran Van Ba, C, Penarete-Vargas, D, Fraisse, L, Cerdan, R, Vial, H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437492/
https://ncbi.nlm.nih.gov/pubmed/22471905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01966.x
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