Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate

BACKGROUND AND PURPOSE: Choline analogues, a new type of antimalarials, exert potent in vitro and in vivo antimalarial activity. This has given rise to albitiazolium, which is currently in phase II clinical trials to cure severe malaria. Here we dissected its mechanism of action step by step from ch...

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Main Authors: Wein, S, Maynadier, M, Bordat, Y, Perez, J, Maheshwari, S, Bette-Bobillo, P, Tran Van Ba, C, Penarete-Vargas, D, Fraisse, L, Cerdan, R, Vial, H
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2012
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437492/
https://ncbi.nlm.nih.gov/pubmed/22471905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01966.x
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