Selection of a trioxaquine as an antimalarial drug candidate

Trioxaquines are antimalarial agents based on hybrid structures with a dual mode of action. One of these molecules, PA1103/SAR116242, is highly active in vitro on several sensitive and resistant strains of Plasmodium falciparum at nanomolar concentrations (e.g., IC(50) value = 10 nM with FcM29, a ch...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Coslédan, Frédéric, Fraisse, Laurent, Pellet, Alain, Guillou, François, Mordmüller, Benjamin, Kremsner, Peter G., Moreno, Alicia, Mazier, Dominique, Maffrand, Jean-Pierre, Meunier, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579890/
https://ncbi.nlm.nih.gov/pubmed/18987321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804338105
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker