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Trichloroethylene Biotransformation and its Role in Mutagenicity, Carcinogenicity and Target Organ Toxicity

Metabolism is critical for the mutagenicity, carcinogenicity, and other adverse health effects of trichloroethylene (TCE). Despite the relatively small size and simple chemical structure of TCE, its metabolism is quite complex, yielding multiple intermediates and end-products. Experimental animal an...

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Publicado en:Mutat Res Rev Mutat Res
Autores principales: Lash, Lawrence H., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254735/
https://ncbi.nlm.nih.gov/pubmed/25484616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2014.04.003
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