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Trichloroethylene Biotransformation and its Role in Mutagenicity, Carcinogenicity and Target Organ Toxicity

Metabolism is critical for the mutagenicity, carcinogenicity, and other adverse health effects of trichloroethylene (TCE). Despite the relatively small size and simple chemical structure of TCE, its metabolism is quite complex, yielding multiple intermediates and end-products. Experimental animal an...

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Detalhes bibliográficos
Publicado no:Mutat Res Rev Mutat Res
Main Authors: Lash, Lawrence H., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254735/
https://ncbi.nlm.nih.gov/pubmed/25484616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2014.04.003
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