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Trichloroethylene Biotransformation and its Role in Mutagenicity, Carcinogenicity and Target Organ Toxicity

Metabolism is critical for the mutagenicity, carcinogenicity, and other adverse health effects of trichloroethylene (TCE). Despite the relatively small size and simple chemical structure of TCE, its metabolism is quite complex, yielding multiple intermediates and end-products. Experimental animal an...

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Библиографические подробности
Опубликовано в: :Mutat Res Rev Mutat Res
Главные авторы: Lash, Lawrence H., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254735/
https://ncbi.nlm.nih.gov/pubmed/25484616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2014.04.003
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