Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model

Lithium has long been used as a treatment for the psychiatric disease bipolar disorder. However, previous studies suggest that lithium provides neuroprotective effects in neurodegenerative diseases such as Parkinson’s disease (PD) and Alzheimer’s disease. The exact mechanism by which lithium exerts...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Lieu, Christopher A., Dewey, Colleen M., Chinta, Shankar J., Rane, Anand, Rajagopalan, Subramanian, Batir, Sean, Kim, Yong-Hwan, Andersen, Julie K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254598/
https://ncbi.nlm.nih.gov/pubmed/25452026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2014.10.032
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