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Age-Related Behavioral Phenotype of an Astrocytic Monoamine Oxidase-B Transgenic Mouse Model of Parkinson’s Disease

We have previously shown that increases in astrocytic monoamine oxidase-B (MAO-B) expression, mimicking that which occurs with aging and in neurodegenerative disease, in a doxycycline (dox)-inducible transgenic mouse model evokes neuropathological similarities to what is observed in the human parkin...

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Hlavní autoři: Lieu, Christopher A., Chinta, Shankar J., Rane, Anand, Andersen, Julie K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542194/
https://ncbi.nlm.nih.gov/pubmed/23326597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054200
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